| 产品名称 |
CSF-1R |
| 来源宿主: |
Rabbit |
| 反应种属: |
Human, Mouse, Rat |
| 克隆类型 |
Rabbit monoclonal |
| 克隆号 |
H0977 |
| 同种型 |
IgG |
| 标记 |
unconjugated |
| 纯化方式 |
Protein A affinity purified. |
| 形式 |
Liquid |
| 存储溶液 |
PBS (pH7.4),0.05% BSA,40% Glycerol. Preservative: 0.05% Sodium Azide. |
| 存储方式 |
Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.Stable for 12 months. |
| 应用 |
WB，IHC, mIHC |
| 使用方法 |
WB 1：1000；IHC 1:200-1:500; mIHC 1:200-1：500 |
| 有效期 |
one year |
| 别名 |
C FMS; CD 115; CD115; CD115; CFMS; Colony stimulating factor 1 receptor; Colony stimulating factor I receptor; CSF 1 R; CSF 1R; CSF-1 receptor; CSF-1-R |
| 免疫原 |
Recombinant protein within human CSF-1-R aa 1-538. |
| SwissProt |
P07333 |
| 细胞定位 |
Cell membrane |
| 分子量 |
Predicted band size: 108 kDa |
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Colony stimulating factor 1 receptor (CSF1R), also known as macrophage colony-stimulating factor receptor (M-CSFR), and CD115 (Cluster of Differentiation 115), is a cell-surface protein encoded by the human CSF1R gene (known also as c-FMS). CSF1R is a receptor that can be activated by two ligands: colony stimulating factor 1 (CSF-1) and interleukin-34 (IL-34). CSF1R is highly expressed in myeloid cells, and CSF1R signaling is necessary for the survival, proliferation, and differentiation of many myeloid cell types in vivo and in vitro. CSF1R signaling is involved in many diseases and is targeted in therapies for cancer, neurodegeneration, and inflammatory bone diseases.
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