Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif. [provided by RefSeq, Oct 2015],
| 产品名称 |
Histone H2A.X (Phospho Ser139) (Y0330) Rabbit mAb |
| 来源宿主: |
Rabbit |
| 反应种属: |
Human,Mouse,Rat, |
| 克隆类型 |
Rabbit monoclonal |
| 克隆号 |
Y0330 |
| 同种型 |
IgG |
| 标记 |
unconjugated |
| 纯化方式 |
Protein A affinity purified. |
| 形式 |
Liquid |
| 存储溶液 |
PBS (pH7.4),50% Glycerol,0.05% BSA,0.05% Proclin 300 |
| 存储方式 |
Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles. |
| 应用 |
WB,IHC,mIHC,IF |
| 使用方法 |
IHC 1:1000-1:4000;mIHC 1:1000-1:4000;WB 1:500-1:2500;IF 1:100-1:500 |
| 有效期 |
one year |
| 别名 |
H2AFX;H2AX;Histone H2A.x;H2a/x |
| SwissProt |
P16104 |
| 细胞定位 |
Nucleus |
| 分子量 |
15kD |
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