This gene encodes an E1-like activating enzyme that is essential for autophagy and cytoplasmic to vacuole transport. The encoded protein is also thought to modulate p53-dependent cell cycle pathways during prolonged metabolic stress. It has been associated with multiple functions, including axon membrane trafficking, axonal homeostasis, mitophagy, adipose differentiation, and hematopoietic stem cell maintenance. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015],
| 产品名称 |
ATG7 (Y0335) Rabbit mAb |
| 来源宿主: |
Rabbit |
| 反应种属: |
Human,Mouse,Rat, |
| 克隆类型 |
Rabbit monoclonal |
| 克隆号 |
Y0335 |
| 同种型 |
IgG |
| 标记 |
unconjugated |
| 纯化方式 |
Protein A affinity purified. |
| 形式 |
Liquid |
| 存储溶液 |
PBS (pH7.4),50% Glycerol,0.05% BSA,0.05% Proclin 300 |
| 存储方式 |
Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles. |
| 应用 |
WB,IHC,mIHC,IF |
| 使用方法 |
IHC 1:100-1:500;mIHC 1:100-1:500;WB 1:500-1:2500;IF 1:100-1:500 |
| 有效期 |
one year |
| 别名 |
Ubiquitin-like modifier-activating enzyme ATG7;ATG12-activating enzyme E1 ATG7;Autophagy-related protein 7;APG7-like;hAGP7;Ubiquitin-activating enzyme E1-like protein; |
| SwissProt |
O95352 |
| 细胞定位 |
Cytoplasm |
| 分子量 |
78kD |
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