The protein encoded by this gene is a member of the homeobox transcription factor family. Members of this family contain a homeobox domain that consists of a 60-amino acid helix-turn-helix structure that binds DNA and RNA. The protein encoded by this gene is conserved across vertebrates and may play an essential role during development. Altered levels of this protein have been reported in cancers of different organs , such as colon , brain , blood , breast , pancreas , liver and esophagus. Alternative splicing results in multiple transcript variants.
| 产品名称 |
PROX1 Rabbit mAb（Y1306） |
| 来源宿主: |
Rabbit |
| 反应种属: |
Human, Mouse, Rat |
| 克隆类型 |
Rabbit monoclonal |
| 克隆号 |
Y1306 |
| 同种型 |
IgG |
| 标记 |
unconjugated |
| 纯化方式 |
Protein A affinity purified. |
| 形式 |
Liquid |
| 存储溶液 |
PBS (pH7.4),0.05% BSA,40% Glycerol. Preservative: 0.05% Sodium Azide. |
| 存储方式 |
Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.Stable for 12 months. |
| 应用 |
WB, IHC, mIHC, IF |
| 使用方法 |
IHC 1:50-1:500;mIHC 1:50-1:500;WB 1:1000-1:5000; IF 1:50-1:500 |
| 有效期 |
one year |
| 别名 |
Prospero homeobox protein 1 (Homeobox prospero-like protein PROX1) (PROX-1) |
| SwissProt |
Q92786;P48437; |
| 细胞定位 |
Nucleus. RORG promotes its nuclear localization. |
| 分子量 |
83kD |
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