CD66b, also known as CEACAM8, is a cell surface glycoprotein that is primarily expressed on granulocytes and is involved in various immune functions. It has been found to be expanded in patients with Waldenstrom macroglobulinemia (WM) and exhibits a unique inflammatory transcriptome. And the main function of CD66b is cell adhesion, cell migration, and pathogen binding. CD66b molecules were localized in lipid rafts, and disruption of lipid rafts or removal of the GPI anchor inhibited the adhesion and activation of eosinophils.
| 产品名称 |
CD66b Rabbit mAb (A3542) |
| 来源宿主: |
Rabbit |
| 反应种属: |
Human |
| 克隆类型 |
Rabbit monoclonal |
| 克隆号 |
A3542 |
| 同种型 |
IgG |
| 标记 |
unconjugated |
| 纯化方式 |
Protein A affinity purified. |
| 形式 |
Liquid |
| 存储溶液 |
PBS (pH7.4),0.05% BSA,40% Glycerol. Preservative: 0.05% Sodium Azide. |
| 存储方式 |
Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.Stable for 12 months. |
| 应用 |
IHC, mIHC |
| 使用方法 |
IHC 1:200-1:1000; mIHC 1:200-1:1000 |
| 有效期 |
one year |
| 别名 |
Carcinoembryonic antigen-related cell adhesion molecule 8, CD67 antigen, Carcinoembryonic antigen CGM6, Non-specific cross-reacting antigen NCA-95, CEACAM8, CGM6 |
| SwissProt |
P31997 |
| 细胞定位 |
Cell membrane |
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